

The flu season has come about, and it's Dr. Mario's duty to use his Megavitamins to heal the people of the land. However, Wario, wanting to have the fame that Dr. Mario has, attempts to steal the Megavitamins, but to no avail. Afterwards, Mad Scienstein and Rudy the Clown (from Wario Land 3) steal the Megavitamins, and both Dr. Mario and Wario give chase.

Join Disney's Mickey, Minnie, Donald and Goofy as they embark on a non-stop adventure full of challenging fun and excitement in Magical Tetris Challenge. Completely addictive, deceptively simple, you'll go wild in a kaleidoscopic shower of falling Tetris pieces in this magical version of the world's most popular video game.

Tetrisphere is a variant on Tetris in which various shapes are shifted across a wrapped three-dimensional grid resembling a sphere, and then destroyed. The objective of the game changes depending on the mode, but generally consists of removing layers of shapes to reach the playing field's core. Despite very little domestic advertising, Tetrisphere enjoyed moderately good sales and a mostly favorable critical reception. Reviewers praised the game's originality and the musical score composed by Neil D. Voss.

There are several key differences in gameplay from the original Tetris. First, in addition to clearing lines, one can also form 4x4 large squares of four pieces to form blocks. When a block is created, it turns solid gold or silver, depending on the makeup of the block. Blocks can only be constructed from whole pieces: if any part of a piece has been cleared, then it cannot be used to form a block. When a line that has pieces from a block is cleared, it earns more points.

Puzzle / Action / Science fiction
Dr. Mario/Puzzle League are recreations of two of Nintendo's most popular puzzle creations. Though Dr. Mario has already been released on the GBA as a Classic NES Series title, the version included in the dual-pack is enhanced specifically for the Game Boy Advance hardware instead of a straight emulation of the original NES title. Puzzle League was originally brought to life as Tetris Attack, but then rebranded on the Game Boy Color as Pokemon Puzzle Challenge a few years back. The GBA version is also enhanced for the GBA's much more capable graphics hardware and was previously an unlockable game via the GameCube - Game Boy Advance Link Cable in Nintendo Puzzle Collection for the GameCube.

Puzzle / Strategy / Arcade / Action / Science fiction
Dr. Robotnik is changing the jolly folk of Beanville into devious little robots that will help rid Planet Mobius of music and fun forever. Group the beans together to help them escape, and compete against Robotnik’s wily henchbots!

Puzzle / Strategy / Fantasy / Science fiction
Dr. Mario is a falling block tile-matching video game, in which Mario assumes the role of a doctor, dropping two-colored medical capsules into a medicine bottle representing the playing field. This area is populated by viruses of three colors: red, yellow, and blue. In a manner and style considered similar to Tetris, the player manipulates each capsule as it falls, moving it left or right and rotating it such that it is positioned alongside the viruses and any existing capsules. When four or more capsule halves or viruses of matching color are aligned in vertical or horizontal configurations, they are removed from play. The main objective is to complete levels, which is accomplished by eliminating all viruses from the playing field. A game over occurs if capsules fill up the playing field in a way that obstructs the bottle's narrow neck.

Puzzle / Arcade / Fantasy / Comedy
Panel de Pon is a game included in Nintendo Puzzle Collection for the Nintendo GameCube, which is the finished version of the cancelled Nintendo 64 video game Panel de Pon 64. The cancelled version ended up being released as Pokémon Puzzle League, albeit it was rebranded and featured characters from the Pokémon anime instead of the traditional fairies from the Panel de Pon franchise. A Nintendo 64 prototype is known to exist, but it is currently publicly unavailable.

Puzzle / Adventure / Action / Fantasy
The Legend of Zelda: Ocarina of Time is the fifth main installment of The Legend of Zelda series and the first to be released for the Nintendo 64. It was one of the most highly anticipated games of its age, and is listed among the greatest video games ever created by numerous websites and magazines. The gameplay of Ocarina of Time was revolutionary for its time, it has arguably made more of an impact on later games in the series than any of its predecessors even though they had the same cores of exploration, dungeons, puzzles and item usage. Among the gameplay mechanics, one of the most noteworthy is the time-traveling system. The game begins with the player controlling the child Link, but later on an adult Link becomes a playable character as well and each of them has certain unique abilities. Ocarina of Time also introduces the use of music to solve puzzles: as new songs are learned, they can be used to solve puzzles, gain access to new areas and warp to different locations. Dungeon exploration is somewhat more puzzle-oriented than in earlier games but they are not too complex.