Arcade Classic No. 4: Defender / Joust1995

A compilation of two classic arcade titles, Galaga and Galaxian ported over to the Game Boy and features original gameplay features. It is also Super Game Boy compatible complete with background borders that replicate their original arcade machine casings.

Like the original Salamander, and as opposed to the Life Force releases, Salamander 2 abandons the selection-bar based power-up system, in favor for a simplified system that focuses on powering weapons up based on specific icons. For example, the player cannot increase his ship speed until a speed icon is picked up; additional speed icons further increase the ship velocity. Several weapons, when additionally upgraded, turn into a 'super' weapon for approximately ten seconds. If the player has the ripple laser, and then gets another icon for it, the player will receive the high-powered Buster ripple for a short period of time. Options have been slightly changed with the arrival of 'option seeds', which are small options that orbit the ship firing only the basic initial shot. Two option seeds can combine into one full option. Moreover, options can also be sacrificed to utilize a short-term homing beam weapon. Several enemy bosses typical to Gradius games return, including the Brain Golem (the first level boss) and the Tetran (the second level boss). There are a total of six levels. Since the game is similar to its prequel, Salamander 2 does not use the Revival Start feature from Gradius (which pushes the player back to a pre-determined checkpoint if a life is lost), many people consider this title to be easier than other titles in the Gradius series due to this. Once the game has been completed, it starts its second-loop at a much higher difficulty. The music is also changed to remixed versions of Salamander's music in some stages. The first player's ship is called Vic Viper while the second player's ship is Super Cobra.

Centipede is a vertically-oriented shoot 'em up arcade game produced by Atari, Inc. in 1980. The game was designed by Ed Logg along with Dona Bailey, one of the few female game programmers in the industry at this time. It was also the first arcade coin-operated game to have a significant female player base. The player defends against swarms of insects, completing a round after eliminating the centipede that winds down the playing field.

A compilation of two classic games, Centipede and Millipede ported over to the Game Boy system with original gameplay. It is also compatible with the Super Game Boy Adapter with backgrounds made to resemble their original arcade casings.

Air Fortress is a video game published in Japan for the Nintendo Entertainment System released in Japan in 1987 and later in North America in 1989. Only a total of 385 copies of the game were shipped to the United States in 1987, and it is believed that only 20 were shipped beforehand as a test run for the system. Within PAL-A regions, it was only released in Australia. This makes the American version of the game very rare.

Arcade Classics: Asteroids + Missile Command is a compilation of the two classic arcade games. This bundle also featured enhanced Super Game Boy support.

Players attempt to shoot demons in a "cosmic carnival" and then pick up the diamonds left behind by them, while dodging shots from enemy skulls. The player operates a laser base at the bottom of a multi-row playfield, using the paddle controller to move it from side to side and the controller's action button to fire a laser beam vertically up the playfield. The player can control how far onto the playfield the beam advances by releasing the button at the desired height. The player receives one point for each demon and ten points for each diamond successfully shot. Points are multiplied by the distance from the base to the target. For example, a demon shot one row above the player is worth one point, while a demon shot four rows above the player is worth four points. In multiplayer mode, the second player operates a laser base at the top of the screen, firing from top to bottom. Again, the second player must shoot demons that match the color of its gun in order to produce diamonds. However, diamonds may be shot by either player. Also, skulls are capable of shooting both up and down the playfield. In select variations of the game, the players can shoot their opponent's laser gun in order to deplete their stock of extra lives. In both single and multiplayer versions, players begin with five lives. One life is lost when the player's laser base is hit by a laser beam fired by a skull or by an opponent, depending on the game variation being played. The game ends when all lives are lost; in multiplayer versions, the surviving player receives a bonus for each life remaining.

The Game Boy port of the 1981 original has features enhancements for the Super Game Boy.